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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8) pab or dibenzocyclooctyne

SKU 57697460541
4.1
EUR245.00 EUR273.00

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Description

or dibenzocyclooctyne

forming an irreversible covalent bond

Product Name Lenalidomide-propargyl Synonyms Lenalidomide-4'-propargyl CAS Number n/a Related CAS Molecular Formula C16H15N3O3 Molecular Weight 297

This compound is a highly potent and efficacious degrader

the labeling efficiency of tetramethylrhodamine maleimides and iodoacetamides is often lower compared to that of other tetramethylrhodamine labeling dyes

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8) pab or dibenzocyclooctyneSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine

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